ATD and Women

Presented: AAFP Boston 1994; AHA 2nd International Conf. Orlando 2005; NLA Scottsdale 2008


The major risk factors for atherothrombotic disease in both men and women are cigarette smoking, dyslipidemia, hypertension, diabetes mellitus, and obesity. The relative mix of these major risk factors differs somewhat between men and women with atherothrombotic disease. This, in turn, may account for the differences in the clinical manifestations of the underlying atherothrombotic disease. Ninety-five percent of all patients (98% of all male and 92% of all female patients) with atherothrombotic disease have at least one of the three prime risk factors: cigarette smoking, dyslipidemia, and hypertension.

These three prime risk factors can be combined into a (global) risk-factor graph that fails to predict only 6% of all patients (2% of male and 10% of female patients) with atherothrombotic disease. The patients who could not be predicted by this risk factor combination are quite old when their atherothrombotic event occurs.

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